PICALM References PICALM gene Ask Anything Homework Help Written by The Information Architects of Encyclopaedia Britannica The Information Architects maintain a master list of the topics included in the corpus of Encyclopædia Britannica, and create and manage the relationships between them. The Information Architects of Encyclopaedia Britannica Britannica AI Ask Anything Learn about this topic in these articles: Alzheimer disease/ Genetic variants…protein of the same name; PICALM, which encodes a protein involved in endocytosis (the cellular uptake of substances); and CD2AP, which encodes a protein that interacts with the cell membrane and may have a role in endocytosis. Read More…protein of the same name; PICALM, which encodes a protein involved in endocytosis (the cellular uptake of substances); and CD2AP, which encodes a protein that interacts with the cell membrane and may have a role in endocytosis. Read More