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Orthoreovirus is a genus of viruses belonging to the family Reoviridae. These viruses are characterized by their lack of an outer envelope, a spheroidal shape, and a size of approximately 70 nanometers. They possess two icosahedral capsids and a core containing segmented, double-stranded RNA.1

While orthoviruses are found in the respiratory and enteric tracts of animals, they are typically not pathogenic in adults. Other genera within the Reoviridae family, such as Orbivirus, Rotavirus, and Phytoreovirus, can cause diseases in mammals, contribute to infant diarrhea, and damage crops like rice and corn. Viruses reproduce only within a host cell, a process involving adsorption, penetration, replication, assembly, and release of progeny viruses.12

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