Obetrol

drug

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Last updated

July 22, 2026

Quick Summary

Obetrol is a reformulated drug that was reintroduced in the 1990s to treat attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. It is a trade name for mixed amphetamine salts, a combination of amphetamine and dextroamphetamine. These stimulants affect the central nervous system, increasing wakefulness and attention while reducing restlessness and impulsiveness.12

Historically, amphetamines were synthesized in the 1880s and later used during World War II to enhance vigilance. They were also used for weight loss and to treat depression. Due to concerns about misuse, regulations were tightened in the late 20th century, leading to a decline in their popularity until Obetrol was reformulated for ADHD treatment.12

While generally safe when prescribed, Obetrol can cause side effects like increased blood pressure and heart rate. Its potential for misuse and addiction is a significant concern, particularly when taken in higher doses than prescribed.12

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History and development
…including the weight loss drug Obetrol. In the 1990s, however, Obetrol was reformulated and introduced to treat ADHD. Because of its potency and long-lasting effects, the drug quickly became a common medication for ADHD, competing with Ritalin, which was the leading treatment at the time.
Read More
…including the weight loss drug Obetrol. In the 1990s, however, Obetrol was reformulated and introduced to treat ADHD. Because of its potency and long-lasting effects, the drug quickly became a common medication for ADHD, competing with Ritalin, which was the leading treatment at the time.
Read More