…intrauterine devices (IUDs), such as Mirena. This particular IUD, once inserted into the uterus, can remain there for up to five years, releasing about 20 micrograms of levonorgestrel daily. Levonorgestrel also is used in various formulations of oral contraceptives, including in combination with estradiol in Seasonale—an extended-cycle oral contraceptive, which…
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