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Merkel cells are specialized cells found in the basal layer of the epidermis, the outermost layer of human skin. They are classified as nonencapsulated corpuscular receptors, meaning they are nerve endings that are not enclosed within a capsule.1

These cells are considered "slowly adapting" mechanoreceptors, which means they respond to specific stimuli, such as touch, and continue to send signals for as long as the stimulus is present. Merkel cells play a role in the sense of touch, contributing to our perception of pressure and texture on the skin's surface.1

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