Meissner plexus

The Meissner plexus, also known as the submucous plexus, is a network of nerves within the wall of the gastrointestinal tract. It is one of two major nerve centers controlling digestive functions, the other being the myenteric plexus (Auerbach's plexus). The Meissner plexus is located in the submucosal tissue, connecting the mucous membrane lining to deeper muscle layers in the stomach and intestines.1

Its functions include regulating the configuration of the gut's inner surface, controlling glandular secretions, altering electrolyte and water transport, and managing local blood flow. While its role in the stomach may be inhibitory, it generally works with the myenteric plexus in the intestines to produce peristaltic waves and increase digestive secretions. The enteric nervous system, which includes the Meissner plexus, operates involuntarily.21