MYCN
Quick Summary
The term "MYCN" refers to the N-MYC proto-oncogene, which is a gene that can contribute to cancer development. Gene amplification, an increase in the number of copies of a proto-oncogene, can lead to excessive protein production. Amplification of the N-MYC gene is observed in approximately 40% of neuroblastoma cases, a type of tumor that commonly affects children and arises in the sympathetic nervous system. A higher copy number of the N-MYC gene is associated with more advanced stages of the disease.12
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