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Langerhans cells are a type of dendritic cell found in the epidermis, the outer layer of the skin. These cells act as "sentinels" of the immune system. They are strategically located to encounter foreign substances, such as bacteria or viruses, that enter the body through the skin.12

Langerhans cells recognize these foreign molecules and then communicate this information to the lymphatic system. This process helps the body mount an effective immune response to combat the invaders. They are also involved in the production of epidermal cytokines, which can influence the body's overall immune responsiveness.2

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