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IgD is one of five classes of immunoglobulins, which are also known as antibodies. It is primarily found on the surface of B cells, a type of lymphocyte crucial for the immune system. While IgD plays a role in the early development of B cells, little of it is released into the bloodstream. Its exact function is not fully understood, but it is thought to be involved in activating B cells when they encounter antigens.1

Immunoglobulins are proteins produced by plasma cells that help the body fight infections. The five main classes are IgG, IgM, IgA, IgD, and IgE, each with distinct properties and functions determined by their structure. IgM is the first immunoglobulin produced by B cells and is effective at clumping bacteria.123

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