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How do eosinophils help defend the body against parasites?
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white blood cell
Blood is made up of multiple components, including red blood cells, white blood cells, platelets, and water-rich plasma.
Eosinophils defend the body against parasites through a collaborative process involving the immune system's antibodies, specifically those of the immunoglobulin E (IgE) class.1
When these antibodies bind to a parasite, such as a flatworm, eosinophils are recruited to the site. The eosinophils attach themselves to the parasite and release specialized chemicals stored within their cytoplasmic granules. These substances are highly effective at damaging the parasite's cuticle, or tough protective body wall, which effectively breaks down the organism's defenses. By targeting the structural integrity of these larger invaders, eosinophils play a critical role in the body's innate immune response.12