Felty syndrome
Quick Summary
Felty syndrome is a rare complication of rheumatoid arthritis that affects the connective tissues. It is characterized by the triad of rheumatoid arthritis, an enlarged spleen, and a low white blood cell count (neutropenia). This condition is considered an autoimmune disorder, meaning the body's immune system mistakenly attacks its own tissues.12
The pathology involves inflammation of the joints and can also affect other organs and small blood vessels. In Felty syndrome, the spleen becomes enlarged, and the body produces fewer white blood cells, increasing susceptibility to infections. While the exact cause is not fully understood, it is believed to involve immune system dysfunction and antibody-antigen reactions.21
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- arthritisAutoimmune arthritis
Felty syndrome is associated with splenomegaly (enlarged spleen), neutropenia (depressed white blood cell levels), and rheumatoid arthritis. Juvenile rheumatoid arthritis is the most common form of childhood arthritis. Disease etiology and clinical course typically differ from that of adult-onset rheumatoid arthritis, and sufferers are prone…
Read MoreFelty syndrome is associated with splenomegaly (enlarged spleen), neutropenia (depressed white blood cell levels), and rheumatoid arthritis. Juvenile rheumatoid arthritis is the most common form of childhood arthritis. Disease etiology and clinical course typically differ from that of adult-onset rheumatoid arthritis, and sufferers are prone…
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joint diseaseRheumatoid arthritis and allied disordersIn Felty syndrome, rheumatoid arthritis coexists with enlargement of the spleen and diminution in the number of circulating blood cells, particularly the white blood cells. Removal of the spleen restores the number of blood cells to normal but has no effect on the arthritis.
Read MoreIn Felty syndrome, rheumatoid arthritis coexists with enlargement of the spleen and diminution in the number of circulating blood cells, particularly the white blood cells. Removal of the spleen restores the number of blood cells to normal but has no effect on the arthritis.
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