E-cadherin
Quick Summary
E-cadherin is a protein that plays a crucial role in cell adhesion, helping cells stick together and maintain their position within tissues. This function is vital for the normal development and operation of multicellular organisms.12
In the context of cancer, a significant aspect of tumor growth and spread (metastasis) involves cancer cells detaching from their neighbors. A key factor in this process is the loss of cellular adhesion. Research indicates that in many epithelial tumors, there is a reduced supply of cell-adhesion molecules like E-cadherin, which normally help keep cells in place. This loss of adhesion is an early step that facilitates cancer cell invasion and dissemination throughout the body.1
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cancerMicroinvasion…that cell-adhesion molecules such as E-cadherin, which helps to keep cells in place, are in short supply.
Read More…that cell-adhesion molecules such as E-cadherin, which helps to keep cells in place, are in short supply.
Read More- cancerInvasion and metastasis
Molecules known as E-cadherin, which changes cell-to-cell adhesion in epithelium, and N-cadherin, which favors cell migration, have been found to be under expressed and overexpressed in invading cancer cells. In addition, a series of important control circuits that operate at the cellular level during the normal development of…
Read MoreMolecules known as E-cadherin, which changes cell-to-cell adhesion in epithelium, and N-cadherin, which favors cell migration, have been found to be under expressed and overexpressed in invading cancer cells. In addition, a series of important control circuits that operate at the cellular level during the normal development of…
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