Britannica AI Icon
Adding us as a Preferred Source tells Google you trust our content, so our articles show up more often in your Google Search, Discover feed, and AI Overviews.
verifiedCite
While every effort has been made to follow citation style rules, there may be some discrepancies. Please refer to the appropriate style manual or other sources if you have any questions.
Select Citation Style
Feedback
Corrections? Updates? Omissions? Let us know if you have suggestions to improve this article (requires login).
Thank you for your feedback

Our editors will review what you’ve submitted and determine whether to revise the article.

External Websites

Caffey syndrome

pathology
Also known as: infantile cortical hyperostosis

Caffey syndrome, a hereditary disease of infants, characterized by swellings of the periosteum (the bone layer where new bone is produced) and the bone cortex of the upper arms, shoulder girdle, and lower jaw. The disease is accompanied by fever and irritability; after a series of periodic exacerbations, it subsides spontaneously.

This article was most recently revised and updated by Robert Curley.