Bowen disease

pathology

Also known as: squamous cell carcinoma in situ

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Last updated

June 22, 2026

Quick Summary

Bowen disease is a form of skin cancer, specifically a type of squamous cell carcinoma in situ, meaning it is confined to the epidermis. It is characterized by persistent red, scaly plaques that contain abnormal keratinocytes upon microscopic examination. While it is considered Stage 0 skin cancer, it can progress to invasive squamous cell carcinoma if left untreated. Causes include chronic exposure to ultraviolet radiation, but it can also arise from exposure to inorganic arsenical drugs. Early diagnosis and treatment, often through minor surgery, are crucial for a good prognosis.12

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skin cancer
Diagnosis and prognosis
…cell carcinoma in situ, or Bowen disease, and is confined to the epidermis. Stage I cancers are 2 cm (approximately 3/4 inch) or less in size; stage II, more than 2 cm. Neither has spread beyond the skin. Stage III cancers have spread to deeper layers of the skin, underlying…
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…cell carcinoma in situ, or Bowen disease, and is confined to the epidermis. Stage I cancers are 2 cm (approximately 3/4 inch) or less in size; stage II, more than 2 cm. Neither has spread beyond the skin. Stage III cancers have spread to deeper layers of the skin, underlying…
Read More