Britannica AI Icon

Barrett esophagus

medical condition
Also known as: Barrett’s esophagus

Quick Summary

Barrett esophagus is a medical condition where the lining of the esophagus is replaced by cells similar to those in the upper stomach. This change occurs in individuals with severe gastroesophageal reflux disease (GERD), a condition involving persistent reflux of stomach contents into the esophagus. The normal squamous cells of the esophagus are replaced by columnar cells, which increases the risk of developing esophageal cancer, typically 10 to 20 years later.12

Risk factors for GERD and subsequent Barrett esophagus include obesity, pregnancy, and hiatal hernias. Symptoms of GERD can include heartburn and regurgitation. While Barrett esophagus itself may not have distinct symptoms, the underlying GERD can cause discomfort. Diagnosis is often made during an esophagogastroduodenoscopy, which allows for visual examination and biopsy of the esophageal lining.13

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

Ask Britannica AI about this topic

Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.