AVPR2

gene

Also known as: arginine vasopressin receptor 2

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Last updated

July 20, 2026

Quick Summary

The AVPR2 gene provides instructions for making the arginine vasopressin receptor 2. This receptor is found primarily in the kidneys and plays a crucial role in regulating the amount of water in the body. When the hormone vasopressin binds to the AVPR2 receptor, it signals the kidneys to reabsorb more water, thus concentrating urine and preventing dehydration. Mutations in the AVPR2 gene can lead to nephrogenic diabetes insipidus, a condition where the kidneys cannot properly respond to vasopressin, resulting in excessive thirst and urination.12

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diabetes insipidus
Types and causes
…mutations in a gene designated AVPR2 (arginine vasopressin receptor 2), which encodes a specific form of the vasopressin receptor, or by mutations in a gene known as AQP2 (aquaporin 2), which encodes a specific form of aquaporin. The vasopressin receptor gene AVPR2 is located on the X chromosome. As a…
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…mutations in a gene designated AVPR2 (arginine vasopressin receptor 2), which encodes a specific form of the vasopressin receptor, or by mutations in a gene known as AQP2 (aquaporin 2), which encodes a specific form of aquaporin. The vasopressin receptor gene AVPR2 is located on the X chromosome. As a…
Read More