APOE3 References APOE3 genetics Ask Anything Homework Help Written by The Information Architects of Encyclopaedia Britannica The Information Architects maintain a master list of the topics included in the corpus of Encyclopædia Britannica, and create and manage the relationships between them. The Information Architects of Encyclopaedia Britannica Britannica AI Ask Anything Learn about this topic in these articles: Alzheimer disease/ Genetic variants…three forms of this gene—APOE2, APOE3, and APOE4—two of which, APOE3 and APOE4, are associated with an increased risk of disease and influence the age of onset of disease. Read More…three forms of this gene—APOE2, APOE3, and APOE4—two of which, APOE3 and APOE4, are associated with an increased risk of disease and influence the age of onset of disease. Read More