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2-keto-3-deoxy-6-phosphogluconate
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2-keto-3-deoxy-6-phosphogluconate

chemical compound
Also known as: KDPG
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Quick Summary

2-keto-3-deoxy-6-phosphogluconate (KDPG) is a chemical compound formed in a specific metabolic pathway in some microorganisms. This pathway is an alternative route for glucose catabolism, meaning how cells break down glucose for energy, especially when certain enzymes needed for glycolysis are absent.1

In this process, 6-phosphogluconate, derived from glucose, loses water in an enzyme-catalyzed reaction to form KDPG. KDPG is then split into pyruvate and glyceraldehyde-3-phosphate, which are intermediates used in the standard glycolytic pathway. This pathway is significant for microorganisms that lack some enzymes essential for glycolysis.1

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.
3 Britannica Sources
  1. metabolism - The phosphogluconate pathway
  2. metabolism - Formation of PEP from pyruvate
  3. metabolism - Hydrolysis of fructose 1,6-diphosphate and glucose 6-phosphate

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