Con Arguments
Con Arguments
(Go to Pro Arguments)Con 1: Women who take birth control pills without medical supervision can put themselves at risk.
While dozens of brand name and generic birth control pills are approved by the FDA for prescription use, only one—the minipill Opill, the progestin-only pill (POP)—has been approved for over-the-counter (OTC) use. This means that the most widely used kind of birth control pill—the combination pill—is not available OTC. Many women, especially young ladies who are less likely to follow the strict timing requirements associated with using the POP, do not understand this.[146] [155]
“It’s generally accepted knowledge that the overall health literacy of the lay [non-medical expert] population is about at the 7th-grade level,” explains gynecologist Jennifer Ashton. She adds that even with one-on-one counseling and explanations about how the Pill works, patients are still confused. [54]
Not understanding birth control pills can have serious and sometimes fatal consequences, especially for women over 35 years old and who smoke or who have a history of diabetes, heart disease, blood clots, cancer, stroke, liver disease, high blood pressure, migraines (and migraines with aura), and/or bladder disease. When a drug is OTC, many users will not even think to contact their doctor, or even the pharmacist, for information because they assume the drug is completely safe. This lack of communication and lack of awareness of side effects due to their health status can put women at risk. [56] [57] [58]
If the Pill is prescribed, the doctor or pharmacist can tell the patient about any possible interactions and prevent bad drug combinations. Drugs that can interfere with birth control pills include the antibiotic rifampin, anti-HIV drugs, anti-fungal medications, anti-seizure drugs, the stimulant modafinil, drugs to treat epilepsy, medications for bipolar disorder, and many herbal remedies including flaxseed and St. John’s wort. Furthermore, the FDA notes the side effects of the Pill include changes in sexual desire, bleeding between periods, sore breasts, headaches, and nausea. [60] [61] [74] [78]
When the Pill is available by prescription only, a doctor usually requires a well-woman exam every one or three years in order to obtain or maintain a birth control prescription. The examination generally includes a Pap smear (the test for cervical cancer that may be combined with HPV screening), a breast exam, and a pelvic exam that, among other things, screens for ovarian cancer and STIs. Additionally, these yearly exams are a good opportunity to check in with the doctor about general wellness and other preventative screenings. When birth control pills are available OTC, women may not check in with their doctors as regularly as they should.[54]
Furthermore, at least 14 percent of women on the Pill are using the drug for non-contraceptive reasons, such as acne and irregular menstrual cycles. That’s a lot of women who could be self-diagnosing medical conditions in a drug store aisle without medical help. [148]
Con 2: OTC birth control pills would be the least effective way to increase use of the best contraceptives.
There are dozens of FDA-approved brand name and generic birth control pills, and the majority will not be available OTC. As of May 2025, only one birth control pill—the minipill Opill—is available OTC, meaning women may choose the progestin-only pill because it’s the easiest to obtain when a prescribed combination pill may be better for them. Plus, only about 0.4 percent of American reproductive-aged women have been prescribed progestin-only birth control pills, or about 2 percent of all women who take the Pill, meaning doctors thought other birth control pills were better options. [73] [76] [77]
Even with OTC options, “Women visiting their pharmacists won’t have access to the most reliable forms of birth control on the market because those methods, such as implantable rods or intrauterine devices (IUDs), will still require a trip to a doctor’s office,” explains journalist Sarah Elizabeth Richards. [75]
Making birth control pills OTC means they would no longer be covered by insurance companies, and women would have to pay for them on their own. With the Obamacare birth control mandate, insured women can access free birth control and well-woman visits without a co-pay. The National Women’s Law Center estimates that 64.2 million insured women had birth control coverage with no out-of-pocket cost. [45] [46] [125] [126]
To combat accessibility barriers, some states are making birth control available without a prescription but not over the counter. In those states, a pharmacist is just required to ask the patient a few questions, and note the patient’s blood pressure and weight. Some states even allow 12-month supplies to be dispensed at once, which has been found to reduce unintended pregnancies by 30 percent and the odds of an abortion by 46 percent. The birth control in these cases is covered by insurance. A study found that 68 percent of women would use birth control if it were available via a pharmacist, and 63 percent agreed the pharmacist consultation was an important step. [66] [67] [68] [127]
Furthermore, women in some states can access birth control via an app or website from private companies. Insurance covers some of these prescriptions, and all that is generally required is a brief consultation to assess risks and appropriate medication, sometimes by video chat. Some services even deliver the birth control to the patient, eliminating the need to stop by a pharmacy. Innovations in birth control pill access like this are better and safer than OTC status. [69] [70] [71] [72]
Con 3: OTC birth control pills could result in more unwanted pregnancies.
The birth control pill is not the most effective form of birth control. Among birth control methods, the Pill ranks seventh in effectiveness. Typical use of the Pill results in eight unintended pregnancies out of 100 women annually. Meanwhile, typical use of copper IUDs, plastic IUSs, female sterilization, contraceptive implants all result in just one unintended pregnancy per 100 women in one year.[49] [149]
Health writer Robin Marty notes that because the more effective options “would require a doctor’s visit and the [OTC] Pill would just require a trip to the store, women may be inclined to use less effective contraception for the sake of convenience.” [50]
Plus, OTC Pills pose a particular risk to teens. The American College of Obstetricians and Gynecologists states, “Adolescents need special attention at every visit for contraceptive services, including comprehensive counseling about sexuality, sexually transmitted disease and emergency contraception.” [51]
Some teens may mistakenly believe that they are at a lower risk of pregnancy just because they have access to OTC birth control, even though they may be taking it incorrectly. This lack of knowledge, combined with increased sexual activity due to mistaken confidence in the inability to get pregnant, can lead to more teen pregnancies. [52]
Increasing access to contraception may increase teen pregnancy rates. Because teens take readily available contraceptives like condoms for granted, they are more likely to ignore the wide availability of an OTC Pill and have sex without any contraceptive protection.[53]
Con 4: OTC birth control pills would decrease privacy.
If birth control pills were available on pharmacy aisles, purchases would be public and subject to the judgment and gossip of anyone in sight. Many people may prefer to keep their contraceptive use between them and their doctors.
“The concept of over-the-counter birth control ignores the grim reality that not all people can just go to a pharmacy and easily purchase birth control. Some face religious and social backlash for buying pills in full view of their pharmacist and people from their community.…Some are young and under a certain state’s law can’t purchase birth control without a parent’s consent. Some are transgender or gender-nonconforming.…The list goes on,” explains Olivia Alperstein of the Congressional Progressive Caucus Center. [63]
Of sexually active teen girls, 59 percent would rather stop getting all reproductive health care services than have to tell their parents about their contraceptive use. But 99 percent of those teens would continue having sex, putting them at risk of pregnancy. Teens want their contraceptive use kept private, and accessing birth control in the middle of a pharmacy where they might run into a neighbor or teacher could stop some teens from preventing pregnancy. [64]
History of the birth control pill
Early birth control
Historically, contraception came in many forms, from condoms to spermicides to cervical caps to the withdrawal method. The use of condoms as contraception dates to approximately 3000 bce, when they were made from fish bladders, animal intestines, linen, or other materials. The Kahun Gynaecological Papyrus (also called the Petrie Medical Papyrus after British Egyptologist Sir Flinders Petrie, who discovered the Egyptian document) is the oldest known medical text and the earliest known discussion of contraception, written around 1825 bce. It suggested vaginal suppositories made of crocodile dung and gum or a honey mixture. [81] [82]
Around 1500 bce the first spermicides appeared, which required soaking linen condoms in a solution and drying them before use. In the 4th century bce Aristotle wrote about women using olive oil as a contraceptive. Women in preindustrial West Africa used plugs made of crushed roots, Japanese women used bamboo tissue, and women of Easter Island used algae and seaweed. [81] [82]
By the 1870s mail-order catalogs like Sears and Roebuck, pharmacies, and rubber vendors sold cervical caps, condoms, diaphragms, douching syringes and solutions, and vaginal sponges. Journalist Lisa Fogarty notes, “Some of the most popular birth control methods and devices in the 1910s included spermicides, douches, an early diaphragm called the Dutch pessary, and ergot pills, which induced abortions.” Most medical professionals, well into the 1960s, were not trained about reproductive health, much less contraception. [82] [83]
Margaret Sanger and Planned Parenthood
In 1914 nurse and social activist Margaret Sanger revolutionized the birth control debate by distributing the 16-page pamphlet Family Limitation, which included technical information about preventing pregnancy and a political statement about a woman’s right to have and use birth control. (Sanger is credited with originating the term birth control.) Due to the existing “obscenity” laws that banned the distribution of material about contraception, printers refused to print the pamphlet; one said, “This is a Sing-Sing job,” meaning the printing of the pamphlet would land him in Sing Sing, a maximum-security prison and one of the oldest penal institutions in the United States (it opened in 1826 in Sing Sing, New York, a village some 30 miles north of Midtown Manhattan that changed its name to Ossining in 1901 to avoid association with the notorious institution). She finally found a Socialist lithographer to print the publication, but only in secret, at night. The pamphlet became an international sensation, revised in 18 editions, in multiple languages. It is considered one of the most significant publications in women’s history. [151]
Fearing arrest and imprisonment, Sanger fled to Canada and then to England, returning to the United States in 1915. Charges against her were dropped, because the prosecutor did not want to make Sanger into a martyr and her trial a public forum for publicizing her beliefs. Sanger then opened the first birth control clinic in the United States on October 16, 1916, in the Brownsville neighborhood of Brooklyn, New York. The clinic offered information from trained nurses on birth control, how to use it, and how the reproductive system works.[81] [82] [84] [85] [90]
Within days of its opening, the clinic was raided, and Sanger and her sister, who helped her at the clinic, were arrested, convicted of violating the 1873 Comstock Act that prohibited the distribution of “obscene” material such as contraception information and devices. They went on trail in January 1917, and her sister was pardoned. Sanger, however, refused a plea deal and served 30 days in a workhouse. Sanger’s conviction was upheld on appeal in 1918, but in his ruling, Judge Frederick Crane also declared that physicians could legally provide contraception to married couples. Sanger’s arrest and trial and Crane’s seminal court ruling gave new life to the birth control movement.[81] [86] [87] [88] [89]
In 1921, Sanger founded the American Birth Control League, a lobbying group, and opened in 1923 in Manhattan, New York, the first legal birth control clinic in the United States, the Clinical Research Bureau (later renamed the Birth Control Clinical Research Bureau); the clinic studied birth control and dispensed contraceptives under the supervision of licensed doctors, and by the 1930s, it was serving over 10,000 patients a year and training thousands of doctors and nurses. By 1929 New York had nine other clinics, and nearly 30 such clinics had opened across the country. In 1930, Sanger opened a clinic in Harlem, New York, staffed by a Black doctor, that had the support of African American leader W.E.B. Du Bois. [82] [89] [90] [91]
By April 1938, there were over 350 birth control clinics in the United States. The birth control industry reported annual sales of over $250 million, and Fortunemagazine declared the industry one of the most prosperous of the decade. Birth control laws varied from state to state: 21 states had legal birth control, but all other states had laws limiting or outright outlawing contraception.[82] [92]
Planned Parenthood was founded in 1942 when the American Birth Control League and the Birth Control Clinical Research Bureau joined forces. [93]
Invention and rise of the pill
In 1950, Margaret Sanger began funding the development of a birth control pill. Reliable birth control could be hard to get at the time. Diaphragms required a doctor’s prescription, and doctors normally required that the woman be married to obtain one. Abortion was illegal and dangerous, and quacks with questionable herbs and contraptions were plentiful. With Gregory Goodwin Pincus and staff doing the research, Roman Catholic doctor John Rock helping with medical trials, and additional funding from Katharine McCormick and drug manufacturer G.D. Searle, the birth control pill was developed. [90]
The development of the Pill was controversial. Sanger courted and obtained the financial and advocacy support of racist eugenicists for her project. The drug was also tested in Puerto Rico and Haiti using methods that were questionable at the time and would not meet modern ethical standards. The Pill was tested on poor women without their knowledge and without knowing about the risks and possible side effects of the drug; some died during the drug trials.[84] [90] [94]
On June 10, 1957, the Food and Drug Administration (FDA) approved Enovid, known thereafter as “the Pill,” for infertility and menstrual irregularities. The FDA required that Enovid include a warning that contraception could be a side effect of the medication. As a G.D. Searle employee, I.C. Winters, said, “It was like a free ad,” because the Pill was being used for contraception anyway.[90]
The FDA approved Enovid again on May 9, 1960, this time for contraceptive use, making it the first FDA-approved contraceptive drug and the first FDA-approved drug that does not treat an illness. Within a year of its approval, 400,000 women (0.4 percent of the U.S. female population) were taking the Pill for birth control, a number that increased to 1.2 million (1.3 percent) the next year, and to almost 6.5 million (6.6 percent) by 1965. [81] [85] [90] [95]
In the early 1960s, David P. Wagner of Geneva, Illinois, distrusted that his wife Doris was taking the Pill correctly. To solve this problem, he drew a calendar on paper and laid each pill out by day, which worked for the Wagners until the paper fell off the dresser. In 1962, Wagner applied for a patent for the circular pill dispenser still common today. [90]
Birth control boom and key Supreme Court cases
In Griswold v. Connecticut (1965), the U.S. Supreme Court ruled that the right of married couples to use birth control was protected under the Constitution’s right to privacy. This ruling did not affect the millions of unmarried women in 26 states who were still prohibited from receiving birth control.[81] [85] [96]
The FDA’s approval of the Pill for contraceptive use in 1960 opened the door for the approval of other birth control methods including intrauterine devices (IUDs) such as Lippes Loop and Copper 7. In 1968, Dalkon shields were introduced, but after 200,000 lawsuits filed on behalf of women who were injured or died as a result of their use, it was taken off the market in 1974. Uncertainty about the safety of birth control methods was fairly common, and the 1970 Nelson Hearings were held in Congress to address the concerns. Although no women were allowed to testify during the hearings, the formulation of the Pill was changed, and the first package insert was required to inform women of the drug’s possible side effects and health risks.[81] [85] [97]
In 1972, with the Baird v. Eisenstadt ruling, the U.S. Supreme Court legalized birth control for everyone, regardless of marital status.[81]
As a result, the birth control market exploded. Low-dose hormone pills were introduced in the 1980s, as were copper IUDs. The 1990s brought the first contraceptive implant, Norplant; the injectable Depo-Provera; a female condom, FC1/Reality; and Plan B, an emergency contraception.[81] [85]
By 1995, only 27 percent of women who used contraceptives used the Pill thanks to increased condom use amid fears of HIV and other sexually transmitted infections (STIs).[98]
21st century
The 2000s saw even more birth control options, including the IUD Mirena, hormonal patch Ortho Evra, vaginal ring Nuvaring, female sterilization Essure, rod implant Implanon, and female condom FC2. [81]
On March 23, 2010, President Barack Obama signed the Patient Protection and Affordable Care Act, which stated contraception is a form of preventative care and would be available without a copay, making most forms of birth control free to women with insurance. On June 30, 2014, the U.S. Supreme Court ruled in Burwell v. Hobby Lobby, Stores, Inc. that corporations run by religious families cannot be required to provide contraception coverage. Additionally, the May 16, 2016, U.S. Supreme Court ruling in Zubik v. Burwell (also known as the Little Sisters case) stated that religious institutions could be exempt from providing birth control coverage to employees. [85] [99] [100]
In February 2025, the FDA approved a new copper, hormone-free IUD, Miudella. Another popular copper IUD is Paragard (approved in 1984); the two differ in copper content and duration of effectiveness. There are also several hormonal IUDs available. [135]
Drugs switched from prescription to over-the-counter status
Between September 9, 1976, and July 16, 2024 (the most recent update to the FDA site), 107 drug ingredients were switched from prescription (Rx) to over-the-counter (OTC) status by the FDA.
| Ingredient [adult dosage] | Brand name examples | Drug category | Date of Rx to OTC switch |
|---|---|---|---|
| Sources: Consumer Healthcare Products Association, “FAQs about Rx-to-OTC Switch,” chpa.org (accessed March 10, 2022) Consumer Healthcare Products Association (CHPA), “Switch List,” chpa.org, August 23, 2023 FDA, “Prescription to Over-the-Counter (OTC) Switch List,” fda.gov, July 16, 2024 | |||
| brompheniramine maleate [4 mg/4-6 hours (oral)] | Dimetapp | antihistamine | September 9, 1976 |
| chlorpheniramine maleate [4 mg/4–6 hours (oral)] | Chlor-Trimeton, Coricidin HBP, Triaminic Cold & Allergy | antihistamine | September 9, 1976 |
| oxymetazoline hydrochloride [0.05 percent aqueous solution (topical)] | Afrin, Neo-Synephrine-12 Hour | nasal decongestant | September 9, 1976 |
| pseudoephedrine hydrochloride [60 mg/4 or 4–6 hours (oral) 240 mg max./24 hours] | Sudafed | nasal decongestant | September 9, 1976 |
| pseudoephedrine sulfate [60 mg/4 or 4–6 hours (oral)] | Drixoral | nasal decongestant | September 9, 1976 |
| xylometazoline hydrochloride [0.01 percent aqueous solution (topical)] | Natru-Vent | nasal decongestant | September 9, 1976 |
| doxylamine succinate [25 mg single dose only (oral)] | Unisom | sleep aid | October 18, 1978 |
| hydrocortisone [0.25 to 0.50 percent (topical)] | Cortaid, Lanacort | anti-itch | December 4, 1979 |
| hydrocortisone acetate [0.25 to 0.50 percent (topical)] | Bactine | anti-itch | December 4, 1979 |
| acidulated phosphate fluoride rinse [0.02 percent fluoride in aqueous solution] | n/a | dental rinse | March 28, 1980 |
| sodium fluoride rinse [0.05 percent aqueous solution (topical)] | Fluorigard | dental rinse | March 28, 1980 |
| stannous fluoride gel [0.4 percent gel (topical)] | GelKam Gel | anti-tooth decay gel | March 28, 1980 |
| stannous fluoride rinse [0.1 percent aqueous solution (topical)] | n/a | dental rinse | March 28, 1980 |
| ephedrine sulfate [0.1–-1.25 percent (topical)] | Pazo Ointment | anorectal vasoconstrictor | May 27, 1980 |
| epinephrine hydrochloride [0.005–0.01 percent (topical)] | n/a | anorectal vasoconstrictor | May 27, 1980 |
| phenylephrine hydrochloride [0.25 percent (topical)] | n/a | anorectal vasoconstrictor | May 27, 1980 |
| chlorpheniramine maleate [12 mg/12 hours (oral timed-release)] | Triaminic 12 | antihistamine | July 23, 1981 |
| phenylpropanolamine hydrochloride [75 mg/12 hours (oral timed-release)] | n/a | nasal decongestant | July 23, 1981 |
| diphenhydramine hydrochloride [25 mg/4 hours (oral)] | Benylin | cough relief and prevention | August 7, 1981 |
| haloprogin [1.0 percent (topical)] | n/a | antifungal | March 23, 1982 |
| miconazole nitrate [2.0 percent (topical)] | Micatin | antifungal | March 23, 1982 |
| diphenhydramine hydrochloride [50 mg single dose only (oral)] | Sominex 2 | sleep aid | April 23, 1982 |
| diphenhydramine monocitrate [76 mg single dose only (oral)] | Excedrin PM | sleep aid | April 23, 1982 |
| dyclonine hydrochloride [0.05–0.1 percent solution or suspension, 1–3 mg as lozenge] | Sucrets Maximum Relief | oral anesthetic | May 25, 1982 |
| dexbrompheniramine maleate [6 mg/12 hours (oral timed-release)] | Drixoral | antihistamine | September 3, 1982 |
| pseudoephedrine sulfate [120 mg/12 hours (oral timed-release)] | Afrinol Repetabs | nasal decongestant | September 3, 1982 |
| triprolidine hydrochloride [2.5 mg/4-6 hours] | Actifed Capsules | antihistamine | November 26, 1982 |
| ibuprofen [200 mg/4–6 hours (oral)] | Advil, Nuprin | internal pain relief/fever reducer | May 18, 1984 |
| dexbrompheniramine maleate [2 mg/4–6 hours (oral)] | n/a | antihistamine | Jan. 15, 1985 |
| diphenhydramine hydrochloride [25-50 mg/4–6 hours (oral)] | Benadryl | antihistamine | Jan. 15, 1985 |
| pseudoephedrine hydrochloride [120 mg/12 hours (oral timed-release)] | Actifed | nasal decongestant | June 17, 1985 |
| triprolidine hydrochloride [5 mg/12 hours] | Actifed 12-hour capsules | antihistamine | June 17, 1985 |
| oxymetazoline hydrochloride [0.025 percent solution/drops (topical)] | Ocuclear | ocular vasoconstrictor | May 30, 1986 |
| pyrantel pamoate [11 mg/kg of body weight, maximum dose 1 g (oral)] | Pin-X | antiparasitic worms | August 1, 1986 |
| povidone iodine sponge [10 percent (new dosage form)] | E-Z Scrub 241 | antimicrobial | Jan. 7, 1987 |
| diphenhydramine hydrochloride [25-50 mg/4–6 hours (oral)] | n/a | anti-vomiting and nausea | April 30, 1987 |
| dexbrompheniramine maleate [3 mg/6–8 hours (oral)] | Drixoral Plus | antihistamine | May 22, 1987 |
| chlophedianol hydrochloride [25 mg/6-8 hours (oral)] | n/a | prevention or relief of cough | August 12, 1987 |
| doxylamine succinate [7.5-12.5 mg/4–6 hours (oral)] | Nyquil | antihistamine | August 24, 1987 |
| loperamide [4 mg, then 2 mg, 8 mg/day (oral)] | Imodium A-D | antidiarrheal | March 3, 1988 |
| hydrogenated soybean oil and lecithin [12.4 g powder in 2–3 oz water; 20 minutes before gall bladder X-rays] | Liposperse | gallbladder emptying drug | February 28, 1989 |
| clotrimazole [1 percent lotion and cream/2 times daily] | Lotrimin AF | antifungal | October 23, 1989 |
| permethrin [1 percent cream rinse] | Nix | lice killer | May 5, 1990 |
| clotrimazole [1 percent cream and 100 mg inserts] | Gyne-Lotrimin | anticandidal | November 30, 1990 |
| miconazole nitrate [2.0 percent cream and 100 mg inserts] | Monistat 7 | anticandidal | March 13, 1991 |
| hydrocortisone+ [above 0.50 percent to 1.0 percent] | n/a | anti-itch | August 30, 1991 |
| hydrocortisone acetate+ [above 0.50 percent to 1.0 percent] | n/a | anti-itch | August 30, 1991 |
| clemastine fumarate [1.34 mg/12 hours] | Tavist-1 | antihistamine | August 21, 1992 |
| clemastine fumarate (in combination with phenylpropanolamine HCl) [1.34 mg/12 hours] | Tavist-D | antihistamine/ decongestant | August 21, 1992 |
| dexchlorpheniramine maleate [2 mg/4–6 hours (oral)] | n/a | antihistamine | December 9, 1992 |
| naproxen sodium [220 mg/4–6 hours (oral)] | Aleve | internal pain relief/fever reducer | Jan. 11, 1994 |
| pheniramine maleatewith naphazoline HCl [0.3 percent; 0.025 percent in solution] | Naphcon A, Opcon A, Ocuhist | ophthalmic antihistamine/ decongestant | June 8, 1994 |
| antazoline phosphatewith naphazoline HCl [0.5 percent; 0.05 percent in solution] | Vasacon A | ophthalmic antihistamine /decongestant | July 11, 1994 |
| famotidine [10 mg, up to 20 mg/day] | Pepcid AC | acid reducer | April 28, 1995 |
| ibuprofen suspension [100mg/5ml for pediatric use, 7.5 mg/kg up to 4 times a day] | Children’s Motrin | internal pain relief/fever reducer | June 16, 1995 |
| cimetidine [200 mg up to twice per day] | Tagamet HB | acid reducer | June 16, 1995 |
| ketoprofen [12.5 mg every 4–6 hours] | Orudis KT | internal pain relief | October 6, 1995 |
| ranitidine [75 mg up to twice per day] | Zantac 75 | acid reducer | December 19, 1995 |
| butoconazole nitrate [2.0 percent cream and applicators (3 days)] | Femstat 3 | anticandidal | December 19, 1995 |
| minoxidil [2.0 percent topical solution] | Rogaine | hair grower | February 9, 1996 |
| nicotine polacrilex [2 mg and 4 mg gum] | Nicorette | smoking cessation | February 9, 1996 |
| nizatidine [75 mg up to twice daily] | AXID AR | acid reducer | May 9, 1996 |
| miconazole nitrate [2.0 percent cream and 200 mg inserts] | Monistat 3 | anticandidal | April 16, 1996 |
| nicotine transdermal system [15 mg patch] | Nicotrol | smoking cessation | July 3, 1996 |
| nicotine transdermal system [21, 14, and 7 mg patch] | Nicoderm CQ, Habitrol | smoking cessation | August 2, 1996 |
| cromolyn sodium [4 percent nasal solution] | Nasalcrom | allergy prevention and treatment | August 2, 1996 |
| tioconazole [6.5 percent vaginal ointment] | Vagistat-1, Monistat 1 | anticandidal | February 11, 1997 |
| ketoconazole [1 percent shampoo] | Nizoral | dandruff shampoo | October 10, 1997 |
| terbinafine hydrochloride [1.0 percent cream] | Lamisil AT | antifungal | March 9, 1999 |
| butenafine hydrochloride [1.0 percent cream] | Lotrimin Ultra | athlete’s foot, jock itch, ringworm | December 7, 2001 |
| guaifenesin extended-release tablet [600 or 1200 mg once or twice a day] | Mucinex | expectorant | July 12, 2002 |
| loratadine [10 mg/day] | Claritin tablets, Claritin RediTabs, Claritin syrup | antihistamine | November 27, 2002 |
| loratadine, pseudoephedrine sulfate [10 mg loratadine, 240 mg pseudoephedrine sulfate daily] | Claritin-D 12-hour extended release tablets, Claritin-D 24-hour extended release tablets | antihistamine /decongestant | November 27, 2002 |
| omeprazole magnesium [20 mg/day] | Prilosec OTC | acid reducer to treat frequent heartburn | June 20, 2003 |
| levonorgestrel [Two 0.75-mg tablets, with the second one taken 12 hours after the first] | Plan B | contraceptive | August 24, 2006 |
| polyethylene glycol 3350 [17 g (scoopful) of powder per day in 8 oz of water] | MiraLAX | laxative | October 6, 2006 |
| ketotifen [0.025 percent ophthalmic solution] | Zaditor | antihistamine eye drops | October 19, 2006 |
| orlistat [60 mg; 180 mg daily max] | Alli | weight loss aid | February 7, 2007 |
| cetirizine HCl & pseudoephedrine HCl [5 mg cetirizine and 120 mg pseudoephedrine] | Zyrtec-D | antihistamine /decongestant | November 9, 2007 |
| cetirizine HCl [1 mg/ml (children’s syrup), 5 mg and 10 mg (tablets and chewable tablets)] | Zyrtec | antihistamine, hives relief | November 16, 2007 |
| lansoprazole [15 mg/day] | Prevacid 24 HR | acid reducer to treat frequent heartburn | May 18, 2009 |
| levonorgestrel [1.5 mg] | Plan B One-Step | contraceptive | July 10, 2009 |
| omeprazole and sodiumbicarbonate [20 mg omeprazole and 1100 mg sodium bicarbonate] | Zegerid OTC | acid reducer to treat frequent heartburn | December 1, 2009 |
| ibuprofen and phenylephrine HCl [200 mg ibuprofen and 10 mg phenylephrine HCl] | Advil Congestion Relief | pain reducer /decongestant | May 27, 2010 |
| fexofenadine hydrochloride [30 mg; 60 mg; 180 mg; 30 mg/5 mL] | Allegra | antihistamine | Jan. 24, 2011 |
| fexofenadine hydrochloride and pseudoephedrine HCl [60 mg; 120 mg] | Allegra-D 12 Hour | antihistamine /decongestant | Jan. 24, 2011 |
| fexofenadine hydrochloride and pseudoephedrine HCl [180 mg; 240 mg] | Allegra-D 24 Hour | antihistamine /decongestant | Jan. 24, 2011 |
| oxybutynin [3.9 mg] | Oxytrol for Women | overactive bladder | Jan. 25, 2011 |
| triamcinolone acetonide [55 mcg/spray, aqueous suspension] | Nasacort Allergy 24HR | intranasal steroid for allergic stuffy nose | October 11, 2013 |
| esomeprazole magnesium [20 mg/day] | Nexium 24HR | acid reducer to treat frequent heartburn | March 28, 2014 |
| fluticasone propionate [50 mcg/spray] | Flonase Allergy Relief | intranasal steroid for upper respiratory allergies | July 23, 2014 |
| budesonide [32 mcg/spray] | Rhinocort Allergy Spray | intranasal steroid for allergic stuffy nose | March 23, 2015 |
| adapalene (sNDA) [0.1 percent gel, once daily] | Differin Gel | acne | July 8, 2016 |
| fluticasone furoate (sNDA) [27.5 mcg/spray] | Flonase Sensimist Allergy Relief | intranasal steroid for upper respiratory allergies | August 2, 2016 |
| levocetirizine dihydrochloride [5 mg] | Xyzal Allergy 24HR | antihistamine | Jan. 31, 2017 |
| brimonidine tartrate [0.025 percent ophthalmic solution] | Lumify | relief of redness of the eye due to minor eye irritations | December 22, 2017 |
| diclofenac sodium [1 percent topical gel, four times per day] | Voltaren Arthritis Pain | topical pain | February 14, 2020 |
| olopatadine hydrochloride [0.1 percent ophthalmic spray, twice daily] | Pataday Twice Daily Relief | antihistamine and redness reliever | February 14, 2020 |
| olopatadine hydrochloride [0.2 percent ophthalmic spray, once daily] | Pataday Once Daily Relief | antihistamine | February 14, 2020 |
| olopatadine hydrochloride [0.7 percent ophthalmic solution, once daily] | Pataday Once Daily Relief Extra Strength | antihistamine | July 13, 2020 |
| ivermectin [0.5 percent lotion, single use tube] | Sklice | lice treatment | October 27, 2020 |
| azelastine hydrochloride [0.15 percent nasal spray, 205.5 mcg/spray] | Astepro | antihistamine | June 17, 2021 |
| alcaftadine [0.25 percent ophthalmic solution, once daily] | Lastacaft | antihistamine | December 10, 2021 |
| mometasone furoate [0.05 mcg/spray] | Nasonex 24HR Allergy | antihistamine | March 17, 2022 |
| naloxone hydrochloride [4 mg nasal spray] | Narcan | treatment for opioid overdose | March 29, 2023 |
| norgestrel [0.075 mg] | Opill | birth control | July 13, 2023 |
| naloxone hydrochloride [3 mg nasal spray] | RiVive | treatment for opioid overdose | July 28, 2023 |
Prescription status of birth control pills around the world
Of the 141 countries listed below, 42 countries (29.7 percent) require a prescription for birth control pills, 47 countries (33.3 percent) officially require no prescription (though 10 require a health screening), and 52 countries (36.9 percent) informally allow (meaning there is no official policy) birth control pills to be distributed without a prescription.
According to the 2020 World Bank population estimates that correlate most closely with the available birth control pill status information, 80.29 percent of the world’s population lived in a country that did not require a prescription for birth control pills: 55.56 percent of the population in a country that officially required no prescription and 24.73 percent that unofficially required no prescription. That leaves about 15.30 percent of the population in countries where the birth control pill required a prescription. (The percentages won’t add up to 100 percent because not all countries have available data.)
Although the vast majority of birth control pills in the United States require a prescription, one pill does not: Opill. The U.S. population stood at 338,016,259 in 2025, which represented 4.22 percent of the world’s population. The prescription status of birth control pills in other countries is listed in the following table. [150]
| Country | Rx required | Available without Rx (health screening required) | Available without Rx (no health screening required) | Informally available without Rx | 2025 Population (millions) |
|---|---|---|---|---|---|
| Sources: OCs OTC Working Group, “Global Oral Contraception Availability,” ocsotc.org (accessed May 14, 2025) World Bank, “Population, Total,” data.worldbank.org (accessed March 17, 2022) | |||||
| Afghanistan | x | 49,474,805 | |||
| Albania | x | 2,551,837 | |||
| Algeria | x | 47,735,685 | |||
| Angola | x | 38,984,796 | |||
| Argentina | x | 45,418,098 | |||
| Armenia | x | 2,963,837 | |||
| Aruba | x | 126,402 | |||
| Australia | x | 27,062,848 | |||
| Austria | x | 9,174,390 | |||
| Azerbaijan | x | 10,694,370 | |||
| Bahamas | x | 415,306 | |||
| Bahrain | x | 1,579,544 | |||
| Bangladesh | x | 170,183,916 | |||
| Belarus | x | 9,460,972 | |||
| Belgium | x | 11,960,170 | |||
| Belize | x | 421,960 | |||
| Bhutan | x | 892,877 | |||
| Bolivia | x | 12,436,103 | |||
| Bosnia and Herzegovina | x | 3,653,499 | |||
| Botswana | x | 2,483,419 | |||
| Brazil | x | 221,359,387 | |||
| Bulgaria | x | 6,737,997 | |||
| Burkina Faso | x | 23,490,300 | |||
| Cambodia | x | 17,230,333 | |||
| Cameroon | x | 31,812,493 | |||
| Canada | x | 39,187,155 | |||
| Cape Verde | x | 618,014 | |||
| Chad | x | 19,674,004 | |||
| Chile | x | 19,091,343 | |||
| China | x | 1,407,181,209 | |||
| Colombia | x | 49,842,298 | |||
| Costa Rica | x | 5,304,932 | |||
| Croatia | x | 4,071,208 | |||
| Cuba | x | 10,059,519 | |||
| Czech Republic | x | 10,838,703 | |||
| Democratic Republic of the Congo | x | 119,038,825 | |||
| Denmark | x | 6,051,491 | |||
| Djibouti | x | 1,013,703 | |||
| Dominican Republic | x | 10,899,292 | |||
| Ecuador | x | 18,479,841 | |||
| Egypt | x | 112,870,457 | |||
| El Salvador | x | 6,839,027 | |||
| Equatorial Guinea | x | 1,853,559 | |||
| Estonia | x | 1,340,478 | |||
| Eswatini | x | 1,145,871 | |||
| Ethiopia | x | 121,372,632 | |||
| Finland | x | 5,550,449 | |||
| France | x | 68,512,806 | |||
| Gabon | x | 2,513,738 | |||
| Georgia | x | 4,877,662 | |||
| Germany | x | 84,012,284 | |||
| Ghana | x | 35,336,133 | |||
| Greece | x | 10,424,536 | |||
| Grenada | x | 114,915 | |||
| Guatemala | x | 18,525,963 | |||
| Guinea | x | 14,374,590 | |||
| Haiti | x | 11,898,812 | |||
| Honduras | x | 9,652,170 | |||
| Hong Kong | x | 7,305,556 | |||
| Hungary | x | 9,827,455 | |||
| Iceland | x | 367,086 | |||
| India | x | 1,419,316,933 | |||
| Indonesia | x | 283,587,097 | |||
| Iran | x | 89,145,704 | |||
| Ireland | x | 5,279,007 | |||
| Israel | x | 9,552,637 | |||
| Italy | x | 60,924,851 | |||
| Ivory Coast | x | 26,378.28 | |||
| Jamaica | x | 2,826,742 | |||
| Japan | x | 122,664,433 | |||
| Jordan | x | 11,312,507 | |||
| Kazakhstan | x | 20,432,662 | |||
| Kenya | x | 55,751,717 | |||
| Kuwait | x | 3,172,511 | |||
| Laos | x | 8,052,913 | |||
| Lebanon | x | 5,707,137 | |||
| Lesotho | x | 2,244,643 | |||
| Liberia | x | 5,563,541 | |||
| Lithuania | x | 2,815,687 | |||
| North Macedonia | x | 2,137,556 | |||
| Madagascar | x | 30,093,073 | |||
| Malawi | x | 22,244,356 | |||
| Malaysia | x | 34,905,275 | |||
| Mali | x | 22,634,423 | |||
| Malta | x | 521,828 | |||
| Marshall Islands | x | 83,037 | |||
| Mexico | x | 131,741,347 | |||
| Moldova | x | 3,578,930 | |||
| Mongolia | x | 3,543,677 | |||
| Morocco | x | 37,698,780 | |||
| Mozambique | x | 34,206,144 | |||
| Namibia | x | 2,852,777 | |||
| Nepal | x | 31,334,402 | |||
| Netherlands | x | 17,833,885 | |||
| New Zealand | x | 5,207,259 | |||
| Nigeria | x | 242,794,751 | |||
| Norway | x | 5,541,823 | |||
| Pakistan | x | 257,047,044 | |||
| Palestine | x | 4,803.27 | |||
| Panama | x | 4,536,008 | |||
| Paraguay | x | 7,604,044 | |||
| Peru | x | 32,768,614 | |||
| Philippines | x | 120,117,029 | |||
| Poland | x | 38,364,679 | |||
| Portugal | x | 10,194,277 | |||
| Romania | x | 17,985,252 | |||
| Russia | x | 140,134,279 | |||
| Rwanda | x | 13,848,766 | |||
| Saudi Arabia | x | 37,172,774 | |||
| Senegal | x | 19,311,233 | |||
| Serbia | x | 6,612,318 | |||
| Singapore | x | 6,080,545 | |||
| Slovakia | x | 5,559,451 | |||
| Slovenia | x | 2,157,163 | |||
| South Africa | x | 61,089,926 | |||
| South Korea | x | 51,486,343 | |||
| Spain | x | 47,336,448 | |||
| Sri Lanka | x | 22,050,561 | |||
| Sudan | x | 51,767,437 | |||
| Sweden | x | 10,643,745 | |||
| Switzerland | x | 8,925,741 | |||
| Syria | x | 24,261,882 | |||
| Tajikistan | x | 10,593,876 | |||
| Tanzania | x | 69,145,464 | |||
| Thailand | x | 70,025,248 | |||
| Togo | x | 9,134,446 | |||
| Trinidad and Tobago | x | 1,410,170 | |||
| Tunisia | x | 12,115,018 | |||
| Turkey | x | 84,625,585 | |||
| Turkmenistan | x | 5,795,896 | |||
| Uganda | x | 50,863,850 | |||
| Ukraine | x | 36,529,111 | |||
| United Arab Emirates | x | 10,093,593 | |||
| United Kingdom | x | 68,751,311 | |||
| Uruguay | x | 3,449,444 | |||
| Venezuela | x | 31,755,435 | |||
| Vietnam | x | 106,688,169 | |||
| Yemen | x | 34,505,496 | |||
| Zambia | x | 21,390,969 | |||
| Zimbabwe | x | 17,472,752 | |||



