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Wyoming, county, western New York state, U.S., consisting of a plateau region bounded by the Genesee River to the southeast. Cliffs as high as 600 feet (183 metres) line the Genesee in Letchworth State Park, which Wyoming county shares with Livingston county. Other waterways include Silver Lake and Tonawanda, Oatka, and East Koy creeks. Forested regions feature a mix of hardwoods. When European settlers first arrived, Iroquoian-speaking Seneca Indians inhabited lands near the Genesee. Located...