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San Bernardino, central city of the San Bernardino–Riverside–Ontario metropolitan complex, seat (1853) of San Bernardino county, southern California, U.S. Located east of Los Angeles, the city lies at the base of the San Bernardino Mountains. It was the site of a Spanish mission (1810) named for St. Bernardino of Siena. The mission was closed in 1834, and the land was later sold to Mormons, who established a fort and laid out a town in 1852....