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The Rupununi River is a tributary of the Essequibo River, Guyana's largest river. It originates in the Rupununi region, within the southern savannas of Guyana, and flows northward. The Essequibo River itself is the largest river between the Amazon and Orinoco rivers, rising in the Acarai Mountains on the Brazilian border and flowing approximately 630 miles to the Atlantic Ocean. The Essequibo's drainage system, including its tributaries like the Rupununi, Mazaruni, and Cuyuni, covers more than half of Guyana. The Rupununi River's headwaters are sometimes confused with those of the Amazon River.123

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