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Piscataquis, county, central Maine, U.S. It comprises a largely mountainous region drained by the Piscataquis, Pleasant, and Penobscot (west branch) rivers. Moosehead Lake (120 square miles [310 square km]), one of the hundreds of lakes and ponds in the county, is the state’s largest lake. Others are Chesuncook, Chamberlain, and Pemadumcook lakes. Mount Katahdin, located in Baxter State Park, rises to Baxter Peak (5,269 feet [1,606 metres]), the highest point in the state and the...