Pamlico Sea References Pamlico Sea ancient lake, United States Ask Anything Homework Help Written by The Information Architects of Encyclopaedia Britannica The Information Architects maintain a master list of the topics included in the corpus of Encyclopædia Britannica, and create and manage the relationships between them. The Information Architects of Encyclopaedia Britannica Britannica AI Ask Anything Learn about this topic in these articles: Lake OkeechobeeA remnant of the prehistoric Pamlico Sea, which once occupied the entire basin including the Everglades, it bears the Hitchiti Indian name for “big water.” Read MoreA remnant of the prehistoric Pamlico Sea, which once occupied the entire basin including the Everglades, it bears the Hitchiti Indian name for “big water.” Read More