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Niles, city, Trumbull county, northeastern Ohio, U.S. It lies along the Mahoning River, about midway between Youngstown and Warren, and is a part of the Mahoning industrial complex. Ruben Harmon, the first white settler (1797), and others discovered deposits of coal, iron ore, and limestone there. James Heaton built a foundry and organized Heaton’s Furnace (1806), which was renamed Nilestown in 1834 (later shortened) to honour Hezekiah Niles, the influential Baltimore (Md.) editor of Niles’...