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New Brunswick, city, seat of Middlesex county, eastern New Jersey, U.S. It lies on the Raritan River, at the terminus of the old Delaware and Raritan Canal, 21 miles (33 km) south-southwest of Newark. The site, first known as Prigmore’s Swamp, was settled in 1681 by John Inian. Called Inian’s Ferry (1713), it was renamed about 1724 for George I of England, who was also the duke of Brunswick. George II granted it a town...