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Mobridge, city, Walworth county, north-central South Dakota, U.S. It lies along the Missouri River (there broadened to form Lake Oahe), about 110 miles (175 km) north of Pierre. Arikara and, later, Sioux Indians were early inhabitants of the area. Settlers began to arrive in the late 19th century, and the site was chosen as the Missouri River crossing point for the Chicago, Milwaukee, and St. Paul Railroad. Telegraph transmissions from the Missouri bridge site were...