At a Glance
Mississippi River
river, United States
Mississippi River, the longest river of North America, draining with its major tributaries an area of approximately 1.2 million square miles (3.1 million square km), or about one-eighth of the entire continent. The Mississippi River lies entirely within the United States. Rising in Lake Itasca in Minnesota, it flows almost due south across the continental interior, collecting the waters of its major tributaries, the Missouri River (to the west) and the Ohio River (to the...