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Lewes, town (parish), Lewes district, administrative county of East Sussex, historic county of Sussex, southeastern England. It lies at a gap in the South Downs and along the River Ouse where it is still tidal. A castle was built there in the 11th century, and its ruins still dominate the town, which grew as a market centre and river port of some importance, although the port later gave way to Newhaven on the coast. In...