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Jacksonville, city, Jackson county, southwestern Oregon, U.S. It lies along Jackson Creek, just west of Medford, in the foothills of the Siskiyou Mountains. It began in 1851–52 as a mining camp with placer gold discoveries along the creek (named for a prospector). By the 1920s mining activities had declined together with the population, and, bypassed by the railroad, in 1927 the city lost to Medford its status (held since 1884) as county seat. Jacksonville has,...