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The Indio River is a river in Nicaragua, flowing for 60 miles (97 km) from the Cordillera Dariense eastward across the lowlands to empty into the Caribbean Sea north of Pearl Lagoon on the central coast. It is one of several rivers in Nicaragua's Caribbean watershed, including the Coco River, Río Grande de Matagalpa, and the San Juan River. The San Juan River, which flows from Lake Nicaragua into the Caribbean, has been a significant waterway for transportation and a point of contention in boundary disputes between Nicaragua and Costa Rica. The city of Indio, located in California, is unrelated to the Nicaraguan river.123

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