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Harlem, district of New York City, U.S., occupying a large part of northern Manhattan. Harlem as a neighbourhood has no fixed boundaries; it may generally be said to lie between 155th Street on the north, the East and Harlem rivers on the east, 96th Street (east of Central Park) and 110th Street and Cathedral Parkway (north and west of Central Park) on the south, and Amsterdam Avenue on the west. In 1658 Peter Stuyvesant, Dutch...