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Georgetown, port city, seat of Georgetown county, eastern South Carolina, U.S. It lies near the Atlantic coast where the Great Pee Dee, Waccamaw, Black, and Sampit rivers enter Winyah Bay. An early Spanish settlement there (1526) was abandoned because of fever. The first English settlement on the site was made about 1700, and the community, formally established in 1734, was named for Britain’s King George II. As a shipping point for indigo, rice, lumber, and...