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Cheboygan, city, seat (1853) of Cheboygan county, northern Michigan, U.S. The city lies along the Cheboygan River as it enters Lake Huron near the eastern end of the Straits of Mackinac. According to some reports, the site was a Native American camping ground until it was settled by Jacob Sammons in 1844. It was first called Duncan, then Inverness, and later Cheboygan, an Algonquian word possibly meaning “Chippewa water” or “the river that comes out...