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Carthage, city, seat of Jasper county, southwestern Missouri, U.S. It lies along Spring River, just east of Joplin. Established in 1842, it was named for ancient Carthage. During the American Civil War, it was a centre of border warfare and was destroyed by Confederate guerrillas in 1861; it was rebuilt in 1866. Nearby lead and zinc mines boosted the economy—at the end of the 19th century Carthage boasted more millionaires per capita than any other...