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Louise Of Savoy (born Sept. 11, 1476, Pont d’Ain, France—died Sept. 22, 1531, Grez, near Fontainebleau) was the mother of King Francis I of France, who as regent twice during his reign played a major role in the government of France. The daughter of Philip II the Landless, duke of Savoy, and Marguerite de Bourbon, Louise married Charles de Valois-OrlĂ©ans, comte d’AngoulĂȘme; they had two children, Margaret, future queen of Navarre and patron of Humanists...