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Jules Hoffmann (born August 2, 1941, Echternach, Luxembourg) is a French immunologist and corecipient, with American immunologist Bruce A. Beutler and Canadian immunologist and cell biologist Ralph M. Steinman, of the 2011 Nobel Prize for Physiology or Medicine for his discoveries relating to the activation of innate immunity (the first line of defense against infection) in the fly Drosophila. Hoffmann’s work provided a vital foundation for subsequent breakthroughs in scientists’ understanding of mammalian immunity. Hoffmann...