- Born:
- 1973?, Israel
Dorry Segev
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Who is Dorry Segev?
Dorry Segev (born 1973?) is an Israeli-born transplant surgeon known for his work in optimizing donor organ use and developing new approaches to organ transplantation, especially for patients with HIV.
Segev's notable achievements include the first U.S. organ transplants between HIV-positive donors and recipients in 2016. He helped pass the Charlie W. Norwood Living Organ Donation Act (2007) and the HIV Organ Policy Equity (HOPE) Act (2013).
His research group has investigated how to make transplants more available, equitable, and cost-effective. Segev also studied desensitization therapy to improve survival among kidney transplant patients with incompatible donors.
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Where was Dorry Segev born and what does he do?
Dorry Segev, born in Israel in 1973, is a renowned transplant surgeon known for his work in advancing equitable organ donation and innovative transplantation methods.
Segev earned degrees in computer science, electrical engineering, and medicine from Rice University and Johns Hopkins University. His research focuses on optimizing organ availability, equitable distribution, and cost-effectiveness. He helped pass the Charlie W. Norwood Living Organ Donation Act (2007), which optimized the use of live donor kidneys through a national paired donor kidney exchange program. Segev also drafted legislation for the HIV Organ Policy Equity (HOPE) Act (2013), which made transplants between HIV-positive donors and HIV-positive recipients legal. In 2016, he performed the first HIV-positive to HIV-positive liver and kidney transplants in the United States.
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What is Dorry Segev known for in the field of surgery?
Dorry Segev is known for his work as a transplant surgeon, particularly his efforts to ensure fair access to donor organs and his innovative approaches to organ transplantation. He is especially recognized for performing the first organ transplants in the United States between HIV-positive donors and HIV-positive recipients in 2016.
Segev helped write and pass legislation for the Charlie W. Norwood Living Organ Donation Act (2007), which optimized the use of live donor kidneys through a national paired donor kidney exchange program. He also investigated desensitization therapy to improve survival among kidney transplant patients who had received organs from incompatible donors. Additionally, Segev helped draft legislation for the HIV Organ Policy Equity (HOPE) Act (2013), which made transplants between HIV-positive donors and HIV-positive recipients legal.
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What are some important achievements of Dorry Segev?
Dorry Segev is an Israeli-born transplant surgeon known for his work in optimizing donor organ use and developing new approaches to organ transplantation.
Key achievements:
- Helped pass the Charlie W. Norwood Living Organ Donation Act (2007), which optimized the use of live donor kidneys through a national paired donor kidney exchange program.
- Investigated desensitization therapy to improve survival among kidney transplant patients who had received organs from incompatible donors.
- In 2016, he performed the first HIV-to-HIV liver and kidney transplants in the U.S. after helping to draft legislation for the HIV Organ Policy Equity (HOPE) Act (2013).
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How has Dorry Segev improved organ transplantation?
Dorry Segev, an Israeli-born transplant surgeon, has significantly advanced organ transplantation through his research and advocacy for equitable access and innovative approaches.
Segev helped to create the Charlie W. Norwood Living Organ Donation Act in 2007, which optimized the use of live donor kidneys through a national paired donor kidney exchange program. He also investigated desensitization therapy to improve survival among kidney transplant patients who had received organs from incompatible donors. In 2016, Segev performed the first HIV-positive to HIV-positive liver and kidney transplants in the U.S., following his work on the HIV Organ Policy Equity (HOPE) Act of 2013, which made such transplants legal.
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What impact has Dorry Segev had on medical research and patient care?
Dorry Segev, an Israeli-born transplant surgeon, has significantly impacted medical research and patient care through his innovative approaches to organ transplantation. His work ensured the equitable and optimal use of donor organs, particularly for patients with HIV.
Segev helped pass the Charlie W. Norwood Living Organ Donation Act (2007), which optimized the use of live donor kidneys through a national paired donor kidney exchange program. He also investigated desensitization therapy to improve survival among kidney transplant patients who had received organs from incompatible donors.
In 2016, Segev performed the first HIV-to-HIV liver transplant in the world and the first such transplant in the U.S., marking the end of a struggle to gain federal approval for these procedures. He also helped draft legislation for the HIV Organ Policy Equity (HOPE) Act (2013), legalizing transplants between HIV-positive individuals.
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Dorry Segev (born 1973?, Israel) is an Israeli-born transplant surgeon who helped advance efforts to ensure the equitable and optimal use of donor organs and who developed innovative approaches to organ transplantation, particularly for patients infected with human immunodeficiency virus (HIV). He was especially well known for having performed, in 2016, the first organ transplants in the United States between an HIV-positive donor and HIV-positive recipients.
Segev earned B.A. degrees (1992) in computer science and electrical engineering at Rice University and an M.D. (1996) at Johns Hopkins University, where he later also completed a residency and a clinical fellowship. While serving as an associate professor in the department of surgery at Johns Hopkins, he received an M.H.S. (2009) in biostatistics and a Ph.D. (2009) in clinical investigation. He also joined the faculty in the school’s departments of epidemiology and biostatistics and later was associate vice-chair for research and director of the Epidemiology Research Group in Organ Transplantation at Johns Hopkins.
Under Segev’s leadership, the Epidemiology Research Group investigated key questions in organ transplantation, including how best to make transplants available to the greatest number of patients while distributing organs equitably and in a cost-effective manner. As part of that work, Segev helped write and pass legislation for the Charlie W. Norwood Living Organ Donation Act (2007), which optimized the use of live donor kidneys through a national paired donor kidney exchange program. The program gave incompatible donor/recipient pairs an opportunity to match with other incompatible pairs.
Segev and colleagues also investigated the ability of a method known as desensitization to improve survival among kidney transplant patients who had received organs from incompatible donors. In desensitization therapy, antibodies that normally would attack a nonmatched organ are filtered from the recipient’s blood. About half of patients on kidney wait lists are predicted to carry antibodies that attack a donor kidney, resulting in transplant failure. Although desensitization therapy required a living donor and was expensive to perform, its ability to overcome the problem of immune rejection meant that transplant could remain an option for the thousands of immune incompatible patients awaiting kidneys.
In 2016, at Johns Hopkins, Segev, assisted by a team of specialists, transplanted a liver and a kidney from a donor infected with HIV to two recipients who were also infected with the virus. The HIV-to-HIV liver transplant was the first in the world (HIV-to-HIV kidney transplant had been accomplished previously in South Africa). The surgery marked the end of a years-long struggle to gain federal approval to perform the lifesaving procedures in the United States. Segev previously had helped draft legislation for the HIV Organ Policy Equity (HOPE) Act (2013), which made transplants between HIV-positive donors and HIV-positive recipients legal for the first time in the country since being banned in the 1980s.