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soprano, the highest human vocal register, extending approximately from middle C to the second A above. A voice with a range approximately from the A below middle C to the second F or G above is termed a mezzo-soprano. Soprano generally refers to female voices, although it is also applied to boy sopranos (also called trebles) and to male castrati singers of the 16th, 17th, and 18th centuries. In music written in four parts, the...