naked mole rat
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What is a naked mole rat?
The naked mole rat (Heterocephalus glaber) is a hairless rodent with wrinkled, pinkish skin, native to the grassy, semiarid regions of East Africa. They live in underground burrows with tunnels that can stretch for miles.
Despite their name, they have about 100 fine hairs that act like whiskers to help them sense their surroundings. Naked mole rats have poor hearing and eyesight and rely on touch and smell to navigate.
They are herbivorous, eating roots and tubers, and practice coprophagy to maximize nutrient absorption. Naked mole rats are eusocial mammals that live in colonies with a queen, workers, and soldiers. They can live for a remarkably long time (10–30 years) compared to other rodents.
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What does a naked mole rat look like?
The naked mole rat (Heterocephalus glaber) is a burrowing rodent native to East Africa, known for its nearly hairless, wrinkled, pinkish skin. Despite their name, they have about 100 fine hairs that act like whiskers, helping them sense their surroundings.
These rodents are small, typically weighing around 28–80 grams and about 7.5 cm long, though size varies depending on their role in their colony. They have small eyes, rendering them practically blind, and they lack external ears. Their bodies are adapted for subterranean life, with short legs for easy tunnel navigation. They also have strong, muscular jaws with four incisor teeth used for digging.
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Where do naked mole rats live?
Naked mole rats live underground in the grassy and semiarid regions of East Africa, including Ethiopia, Kenya, Somalia, and Djibouti. They create extensive networks of tunnels that can be up to 2 meters (6.5 feet) deep and 4 km (2.5 miles) long. These tunnels connect chambers used for nesting, nursing, food storage, and other functions. Naked mole rats live in colonies of up to 300 individuals in these arid parts of East Africa.
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How do naked mole rats survive underground?
Naked mole rats survive underground through a variety of adaptations. They dwell in subterranean burrows with extensive tunnel networks reaching up to 2 meters (6.5 feet) deep and 4 km (2.5 miles) long, which they create by gnawing away dirt with their large incisor teeth.
Their bodies have adapted to underground life with small eyes and degenerated hearing, relying instead on touch and smell to navigate tunnels. Fine hairs on their bodies act as whiskers, sensing vibrations and air currents. They eat roots and tubers, reingesting their feces to maximize nutrient absorption, and they don't need to dig for water.
Additionally, naked mole rats possess a unique ability to survive in low-oxygen conditions by switching to a modified pathway that relies on the sugars fructose and sucrose.
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What is special about the way naked mole rats live in colonies?
Naked mole rats are among the few truly eusocial mammals. They live in large colonies with a strict hierarchical structure, where most individuals cooperate to support the few that reproduce.
A queen leads the colony and is the only breeding female, mating with a few males and producing multiple litters per year. The other colony members are workers or soldiers. Workers dig tunnels, gather food, and care for pups. Soldiers are larger and defend the colony.
Their eusocial behavior also helps with thermoregulation, as naked mole rats can't maintain a stable body temperature and huddle together to conserve heat.
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Why are naked mole rats important for scientific research?
Naked mole rats are valuable for scientific research because of their unique traits, including cancer resistance, slow aging, and pain resistance. Their long life spans, which can range from 10 to 30 years, defy the Gompertz law, which states that the risk of dying increases exponentially with age.
These animals also possess a unique ability to survive in low-oxygen conditions due to a modified sugar processing pathway. The sugar molecule hyaluronan in naked mole rats is much larger than in other animals, preventing cells from forming tumors.
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naked mole rat, (Heterocephalus glaber), burrowing member of the rodent family Bathyergidae, named for its wrinkled pinkish skin and hairless bodily appearance. Their broad heads contain strong, muscular jaws that support four incisor teeth that are used for digging. They are renowned for their long life spans, low cancer rates, and colonial habit. Contrary to what their name suggests, naked mole rats have about 100 fine hairs on their skin that function like whiskers to help them feel their surroundings.
Naked mole rats can be found underground in the grassy and semiarid regions of East Africa, including Ethiopia, Kenya, Somalia, and Djibouti. They inhabit subterranean burrows formed by an extensive network of tunnels that may range up to 2 metres (6.5 feet) deep and 4 km (2.5 miles) long. They create these tunnels, approximately 4 cm (1.5 inches) in diameter, by gnawing away dirt with their large teeth and sweeping it up to the surface in an assembly-line fashion. The tunnels connect chambers used for nesting, nursing, food storage, and other functions.
Natural history
Naked mole rats are typically 7.5 cm (3 inches) long and weigh approximately 28–42 grams (1–1.5 ounces), although their size can be larger depending on their role in the colony. Their bodies have developed several adaptations that allow them to live in subterranean habitats. They possess small eyes, which renders them practically blind. They do not have external ears, and their inner ears lack structures that allow for cochlear amplification (a process that boosts sound before it reaches the brain), which contributes to degenerated hearing. Naked mole rats rely on their other senses, particularly touch and smell, to navigate the tunnels. The fine hairs on their bodies function as whiskers to sense vibrations and air currents in the burrow, and their short legs allow them to easily navigate the tunnels. One-quarter of a naked mole rat’s muscle mass is contained in the jaw, while nearly one-third of its brain’s somatosensory cortex, the area associated with the sense of touch, is devoted to its teeth.
Naked mole rats are herbivorous, and they eat the parts of plants growing beneath the surface, such as roots and tubers. If a large tuber is found, naked mole rats may eat the interior and leave the outside mostly intact, allowing it to grow back and become a consistent food source. They do not dig for water to drink, as their diet provides sufficient moisture. Because digging for food is such an energy-intensive process, naked mole rats practice coprophagy: they reingest their feces in order to maximize the amount of nutrients absorbed from their food.
Naked mole rats are one of the only truly eusocial mammals—that is, they live in large colonies defined by a hierarchical social structure in which nearly all of the individuals cooperate to aid the relatively few individuals that reproduce. Colonies are led by a female naked mole rat called the queen, which is the only female that reproduces. The queen mates with a small number of males and produces litters up to four or five times yearly. Although the average size of a litter is approximately 12 pups, this number is quite variable and can reach as high as about 30 pups—one of the largest litter sizes for any mammal. The other naked mole rats in the colony function as either workers or soldiers. Workers are approximately 7.5 cm long and 35 grams (1.25 ounces) in weight; they dig tunnels, gather food, and care for pups. Soldiers, by contrast, use their comparatively larger size, approximately 55 grams (2 ounces) in weight, to protect the queen and the colony from snakes and other predators. The naked mole rat’s eusocial nature also comes in handy with respect to thermoregulation; unlike many other mammals, naked mole rats are unable to maintain a stable body temperature and sometimes huddle together in large masses to conserve their body heat.
Naked mole rats can live exceptionally long lives, with life spans estimated from 10–30 years, far longer than other small rodents. Studies on naked mole rats have revealed that they defy the Gompertz law, a mathematical equation developed by British mathematician Benjamin Gompertz that posits that the risk of dying increases exponentially with age. While this risk of mortality doubles every eight years after age 30 in humans, a naked mole rat’s chance of dying appears to stay constant for the entirety of its life. (See also aging.) The International Union for Conservation of Nature and Natural Resources has classified Heterocephalus glaber as a species of least concern.
Cancer resistance
Research has revealed that the source of these lengthy life spans may be the naked mole rat’s lack of tumorigenesis, the formation of malignant tumours. Although a few cases of cancer have been reported in naked mole rats, their incidence of cancer is significantly lower compared with similarly sized animals as well as humans. The key to their cancer resistance may derive from the sugar molecule hyaluronan, which keeps cells from clumping together to form tumours. Hyaluronan molecules are present in all animals, but they are extremely large in naked mole rats (about five times larger than those found in mice, rats, and humans), and these supersized molecules are not broken down by enzymes as rapidly as they are in other animals.


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