Who were Edwin Augustus Atlee and Samuel Mathews?

Edwin Augustus Atlee and Samuel Mathews were American medical researchers who published dissertations on the clinical use of music in the early 19th century—Atlee in 1804 and Mathews in 1806. Both men studied under the prominent American physician Benjamin Rush, who was a well-known advocate for utilizing music in clinical settings. Their work contributed to the early investigation of the physiological changes that music could effect, a period during which the scientific method was increasingly applied to the study of music therapy.1