Which Indigenous languages of Mesoamerica are classified as language isolates?

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In the context of the Indigenous languages of Mesoamerica, language isolates are defined as languages that have no known relatives. The languages classified as isolates within Mesoamerica are:123

  • Cuitlatec: An extinct language formerly spoken in the state of Guerrero.3
  • Ikoot: Also known as Huave, this language is spoken in the state of Oaxaca.13
  • Tarascan: Also known as Purépecha, this language is spoken in the highlands of Michoacán.23

While other languages in the broader Middle American region, such as Seri, are also considered language isolates, they are categorized as non-Mesoamerican.3