How is relative risk calculated from the incidence of disease in exposed and unexposed groups?
In epidemiology, relative risk is a measure of association used to quantify the strength of the relationship between an exposure and a health outcome, such as a disease. It is calculated by dividing the incidence of the event in an exposed group by the incidence of the event in a baseline (unexposed) group.1
The formula is expressed as:
For example, if 10 out of 1,000 exposed individuals develop a disease and 2 out of 1,000 unexposed individuals develop the same disease, the relative risk is calculated as . This indicates that those in the exposed group are five times more likely to develop the disease than those in the unexposed group. A relative risk of 1 suggests no association, while a value greater than 1 indicates an increased risk and a value less than 1 suggests a protective effect.1