Why do denser suspended particles move toward the outside of a spinning centrifuge?

In a centrifuge, denser suspended particles move toward the outside because the device generates a centrifugal force that acts as a substitute for gravity.1

According to Newton’s first law of motion, objects in motion tend to travel in a straight line. When a mixture is rotated, the centrifuge forces these particles into a curved path. Because the particles possess mass, they exert an outward pull—the centrifugal force—in an effort to continue moving in a straight tangential course.1

The net force driving a particle toward the periphery is the difference between the centrifugal field acting on the particle and the opposing buoyancy of the surrounding liquid. Consequently, particles that are denser than the suspending liquid experience a greater outward pull than the liquid itself, causing them to migrate toward the outer wall of the spinning vessel.1