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Why is plasma used during some blood transfusions?
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blood transfusion
Depiction of a direct blood transfusion performed in 1882.
Plasma is used during blood transfusions primarily to replace clotting factors in patients who have specific medical needs. It is a critical component for individuals suffering from bleeding disorders, liver disease, or those experiencing massive hemorrhage who require the restoration of their blood's ability to coagulate.12
Beyond its role in coagulation, plasma and its derivatives are utilized for other therapeutic purposes:
- Fluid and Protein Balance: Albumin, a protein derived from plasma, is used in cases involving shock, burns, or severe fluid imbalances to help maintain proper osmotic pressure and blood volume.32
- Immune Support: Immune globulin, which consists of concentrated antibodies, is administered to provide protection against certain infections or to treat immune-related conditions.2
By separating plasma from whole blood, medical professionals can provide targeted treatments tailored to a patient's specific deficiency rather than transfusing unnecessary components.24