Why can people distinguish between caraway and spearmint even though their odor molecules are mirror-image forms of carvone?

Created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.

People can distinguish between caraway and spearmint because they are composed of different enantiomers of the molecule carvone. While enantiomers are mirror-image forms of the same molecule, they are chiral, meaning they are not superimposable on one another.12

The human olfactory system functions through specific olfactory receptor proteins that act like a lock and key; a molecule must fit into a specific "pocket" on the receptor to trigger a response. Because biological systems are themselves chiral—composed of specific, handed amino acids—the receptors interact differently with each mirror-image form of carvone. Just as a right hand interacts differently with a labeled object than a left hand would, the two forms of carvone fit into different receptor pockets, stimulating distinct sets of receptor cells and allowing the brain to perceive them as unique scents.312