Britannica
Sources used in this answer
Why can high-energy megavoltage radiation treat tumors deep inside the body?
Created from Britannica articles
using AI.
AI can make mistakes, so verify using Britannica articles.
radiation therapy
External beam radiation therapy (also known as external beam teletherapy, or long-distance therapy) being delivered using a machine known as a linear accelerator.
High-energy megavoltage radiation is effective for treating deep-seated tumors because its high energy level allows the radiation beam to penetrate through surface tissues to reach internal targets.1
In contrast to older orthovoltage X-rays (140β400 kilovolts), which deposited significant energy at the skin level and caused severe burns, megavoltage beams (exceeding 1,000 kilovolts) deliver a much lower dose to the skin. This "skin-sparing" effect, combined with the beam's ability to travel through the body to reach deep-seated growths, makes modern radiation therapy a safer and more precise tool for oncology. These beams are typically generated by linear accelerators that accelerate particles to produce the necessary therapeutic energy.1