Which structures make up a mammalian nephron?

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A mammalian nephron is the functional unit of the kidney, responsible for producing urine through the processes of filtration, reabsorption, and secretion. Each nephron is composed of the following primary structures:123

  • Renal Corpuscle: This is the filtration unit, consisting of a cluster of capillaries called the glomerulus enclosed within a double-walled, cuplike structure known as Bowman’s capsule.142
  • Proximal Convoluted Tubule: Located in the renal cortex, this section follows the renal corpuscle and is the site where a significant portion of water and valuable solutes are reabsorbed into the blood.253
  • Loop of Henle: A long, U-shaped segment that descends into the medulla and returns to the cortex. It plays a critical role in the concentration of urine through the recovery of water and sodium chloride.653
  • Distal Convoluted Tubule: Following the loop of Henle, this tubule is involved in further reabsorption of salts and water before the fluid enters the collecting tubule.53