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Which neurotransmitters affect hippocampal activity?
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hippocampus
Learn about Henry Molaison (better known as “patient H.M.”), whose short-term memory loss following a lobotomy helped researchers to understand how brain structures are related to brain function.
The hippocampus receives input from several modulatory neurotransmitter systems that influence its activity. These include:
- Serotonin: A neurotransmitter system that provides modulatory input to the hippocampus.1
- Norepinephrine: This system also contributes to the modulation of hippocampal activity.1
- Dopamine: This neurotransmitter system is another source of modulatory input to the region.1
- Acetylcholine: The hippocampus receives cholinergic input from the medial septum, which is essential for regulating the physiological state of the hippocampus and setting the theta rhythm, a critical oscillatory rhythm for hippocampal function.1