Which joints are commonly affected by rheumatoid arthritis?

Rheumatoid arthritis is a chronic condition characterized by inflammation of the peripheral joints. While the disease can involve almost any movable joint in the body, it typically attacks the joints of the hands and feet first, often in a symmetrical pattern—meaning it affects the same joints on both sides of the body.123

As the condition progresses, it frequently spreads to other areas, with the wrists, knees, and shoulders being particularly susceptible. The disease process involves inflammation of the synovial membranes, which can lead to the destruction of cartilage and eventual joint deformity or immobility.23